I like to shoot and hunt with different rifles. Over many years I have used a variety of calibers on deer including my 338 Win. If you are a handloader, the 338 is a versatile cartridge. I found a deer load with the 200 gr Nosler Ballistic Tips that my rfle likes fine. The 338 doesn't turn deer into hamburger, the wounds look like what my 30-06 does. I have used the 260, 7TCU rifle, 6.5x55, 7-08, 7x57, 30-06, 300 Weatherby, and a .357 mag Model 94 on deer, and I say it's all good. If you want to use them they all work on deer when used within the capabilities of each caliber.
My 338 is a beautiful Model 70 Super Grade, I can't take it and go elk hunting every year, but I also can't stand to leave it in the safe. I take it hunting and enjoy it. If someone wants to use whatever, it's all about your enjoyment of the hunt. Which rifle you pick has alot to do with that.