because the .22-250 is capable of 400 yd' harvests on varmints i'd consider the scope you've asked about.
that 50 mm objective helps give you a little more detail when dialing-up the power. that extra detail may help with doping the wind if the 'mirage' is not too much for the higher magnification on a given day.
i have dealt with our one sponsor 'SWFA' and it has repeatedly been a pleasant experience. their prices are reasonable and the service is great.
i hope it works out well for you with that Ruger. i can't find much wrong with buying a Model 77 Mk II, and would definitely enjoy working with one of their VT's.....
ss'