For all my handguns, 38 special and smaller, I use RBCD, Performance Plus.
It is a very light, high velocity, totally fragmenting soft point. The 38 special is only 60 gr, but, with a muzzle velocity of over 1700 fps. When the bullet hits the target it is followed by a nylon ball that shatters the lead about like a water balloon. The result is complete energy absorbed by the target, and a permanent cavity in flesh of about 7" dia x 10" deep.
As a fringe benefit, the recoil is minimal due to the light projectile. This allows you to bring the muzzle back on target almost immediately for subsequent shots.