I`m a Leupold fan. My long gun for coyote is a .22-6mm. With it I`m pushing an 80 gn. Sierra MK bullet to 3,600 fps. and maybe a little more, have settled on best load yet. I just picked up an 8.5 x 25 Leupold with mil dots for it. I`ve been using a 24 X and dialing in the range. I wanting alot more than 300 yrds. though. So far I`m 1 shot 1 kill at 350 and the only group I shot at 500 yrds. was 3 1/4 in. With your 250 you should be good to 600 yrds. with a range finder and and carrying a drop chart or you could use a mil dot radical and not have to dial in your range. I would recommend the 6 x 18 VX 11 since they put 1/4 clicks in them.