If that 46gr of IMR4350 is for 140gr bullets, that's a max load, certainly not a place to be starting!!
If it's for 120gr bullets, work up some, I can't see how someone can expect to pick a random load and expect a lot from it, you may get lucky, but more than likely, you'll just waste your time, powder and bullets!! While I've never worked a load at 25yds, I've always been able to shoot better than "patterns" at 100yds, with very few exceptions. Load work up is just that, start at or near the start load and work up, I do ½gr increments, some use 1gr increments, but I'll tell ya right now, I've had loads that went from 1½"moa to ½"moa with just a ½gr change, many times!! Usually I'll load 3 shots each in ½gr increments from the recommended start load right up to the max, that could be anywhere from 18 to 30 rounds total, depending on the load, if the spread is only a few grains, I'll work the last 1 grain in .2gr increments, and for a small case like the Hornet, the entire load is worked in .1gr increments.
You can also use a load ladder where you load 20 rounds in small increments, .2gr or.5gr increments, you shoot all rounds at the same target and carefully mark where each round struck on a target at your bench, the accurate load to concentrate on will be where the tightest cluster of impacts occur.
http://www.mikeswillowlake.com/ladder%20test.htmTim
