OK, since I am bored---
Define "best"?
If you mean fit and finish, then an early #27 or Python would be pretty close. The ultimate gun, not listed here, was the "Korth" revolver, which I believe was made in France. I examined one in the early 80's, and its fit and finish was the best I have ever seen on a revolver. It sold for $1500.00 back when a Python was like $250.00
If you mean accuracy, then that would be the Dan Wesson. When long range shooting at little steel pigs and chickens, and such was really popular, DW was the gun to have. I guess it had something to do with a quality barrel, along with user adjustable barrel tension and cylinder gap.
Durability? That would be Ruger. Rugers tend to be built like AK-47's - A little rougher then some, but strong. I did a lot of double action revolver shooting when I was younger, I mean a real lot, and I never seen a Ruger fail. Smiths were pretty good, DW's would wear hands and tend to get a little sloppy with a lot of DA use, and Pythons tended to break a lot. The Python action, as smooth as it was, was an old design, with lots of flat springs and less then durable parts. If I were offered any revolver, and my life depended on shooting 10,000 rounds, fault free, it would be a Ruger
Handling / feel in your hand? This is the most subjective one, but I have always liked the way the Smith L frame feels. Good combination of balance, size, and pointability. Combine that with a durable and easy to work on action, a double action pull that smooths right up with a little use, a great S/A pull, very good accuracy, and usualy high S&W quality, and you have a winner - A gun that is best, at most, in one catagory, but very good in all others for the over all win.
Larry