I've been shooting the 45 LC for almost 30 years, it's still my favorite caliber. It will take deer and critters of all kinds. I started out with black hawks pushing the 45 LC to the limit when I was younger, using both jacketed and cast bullets and was not to bright about my loads when younger either. I've learned a lot. Now probably won't ever buy a jacketed bullet in 45 LC again, I shoot all cast bullets now and nothing much more than around 900 fps out of a handgun, anything more I need will be a different caliber, but that is just me these days. I love this caliber and really like the fact that there are rifles out there of all different kinds for the 45 LC too. I think it's a great caliber for hunting within it's limits and there is some power there if you wish to load it up in Rugers or certain rifles. I see NEF has a carbine now in 45 LC that looks kind of like it's big brother NEF Buffalo Classic, wouldn't mind having a look at this single shot for fun too. A Marlin rifle would be an excellent choice for 45 Colt. You would not regret it.