I use Varget powder (near max) and 165 gr Sierras in my .308. One year I took a bear, antelope and whitetail with one shot each using that load. I also got good accuracy with IMR 4895 but the Varget gave higher numbers on the chrony. When I tried to match the velocities of the the Varget with the 4895, the groups opened up and I started getting cratered primers. From what I have read, the .308 will shoot a lot of different powders well.