I have a couple of the Nikon 4X rimfires from Wal-Mart and they have been great on my 22's, and they may be strong enough to handle centerfire recoil, but I would put in a plug for spending an extra $50 at Wal-Mart on the 3-9 Nikon Prostaff. This is an excellent scope, and you have the versatility of a wider magnification range. I have one on my handi-rifle in .223 and love it.