When it comes to my home and family I like both!
Stopping power has been argued too much for my tastes. Facts, the GI's that carried the 1911 45's complained about recoil, not that it didn't put bad guys down. Fact, today GI's complain that a 9mm doesn't put the bad guys down, but at least they have plenty of ammo to shoot them again with. Obviously wars claim more lives with guns than anything else, so I'll take the GI's word for it.
All that said I have a Springfield XD 45 by my bed. It hold 13 rounds of 45ACP and I've got some spare mags, not that it'd ever be needed. Everyone likes to think they'll never miss a shot, that's ego talking. Realty is if you wake up in the middle of the night because of bad guys bigger bullets are better and the more the merrier.