My Sendero in 300 WM gets a tweak more out of RL-22 and RL-25 over IMR 4350 or 4831. Both RL's were more accurate. RL-25 gave about 35 fps more velocity over RL-22. Shooting new Nosler 200 gr. Accubond at 3,000 fps with no pressure indicators. In fact still below max loads where the 300 WM generally shines best. Just shot at 200 and both loads were well within 2" off cross sticks (elk hunt this fall so I am practicing as I expect to shoot). Historically, I have always done better with RL-22 and RL-25 in belted mags. Meters great and settles in cases nicely. I would definitely try them and go with RL-22 first since you will be most likely using lighter weight bullets in that hand cannon. Gotta believe the muzzle blast is a bit snorky though.
Muddy