My lease is full of rattlesnakes so I carry my Single Six with 4 JHP mags and two CCI shotshells ready to go first. I was out there this morning, just checkin' tracks, and put out a 6"X8" target to "pattern" the shot. At six feet the shot completely covered the cardboard. In the center of the pattern was a 22 cal sized impression, from the little shot cup cap, I guess. One shot ain't exactly a scientific study (I only had one piece of target-grade cardboard in the truck) but there ya have it. I'm sure though, that beyond six feet the pattern falls apart REAL quick.