I have taken two whitetail deer with the LaserCast RNFP, only mine were the 200grn ones. One from a 5&1/3 in Uberti revolver, and one from a Puma lever action carbine with a 20 in barrel. Both were standing shots about 60 to 75 yds, and both penetrated both front shoulders and exited the other side. Both deer were knocked down and flopped a bit before dieing, but didn't run.
The load used was a full case of compressed American Pioner Powder, (A Black Powder sub) under a 200grn RNFP. It was about 37 to 38 grn equivalent to equivalent load.
Both bullets exited the animal and were not recovered. I was satisfied with the performance of both guns and bullets. Both deer were about 150lb average whitetail does.
I realy love BP and BP Sub shooting!!!!
Greeenriver
PS: This load gives about 800 fps in the pistols, and a little more in the rifles