Not that he needs me to (after all 1. he's right, 2. it's HIS web site) but I'll back up GB on this. I have personally asked JD about doing a 375 JDJ in a handi and he flat said "not in one of those rifles". Hmmm, nuff said, point taken, idea dropped.
Also to point out a subtle comment GB made, that didn't seem to get picked up on.
There WILL be a difference in SOME dimension of the wildcat 221-300 or any similar reamers to keep it legally NOT the 300 Whisper. Once this change is made, the 300 whisper brass may or MAY NOT chamber safely.
There's a good article in the current issue of Shooting times on the 338 Federal. The author mentions, and shows pics, of an old mauser he'd long ago had converted to the 338-08. same thing right? The 338 Fed ammo would NOT chamber in his 338-08 rifle dureto differences in the throat area.
You'd be stuck using 221-300 special dies, making ALL your own brass. But it's your money.