Bowhunter,
I've owned and shot my .45 Colt 1875 Uberti for over 25 years and find it to be a durable, well-made clone of the Remington revolver. My shooting buddy has one in .37 Magnum. We find field accuracy to be all it needs to be and they are totally reliable. The timing and endshake remain as tight as when it was new. The fixed sights will take se load development to get it to shoot to point-of-aim.
If I had a complaint, it would be that the chambers are a bit oversize by American standards. Both factory loads and handloads produce a pronounded bulge ahead of the rims. The chamber throats are also a bit oversized, but not enough to prevent the gun from giving 2"-2 1/2" groups at 25 yards.