I've shot a number of deer with the 270. The only real 'bang-flop' I've had is when I broke the backbone shooting downhill at a moving deer. On the other hand, the only deer that ran any significant distance was one I shot running away. I broke the left rear leg and the bullet lodged in the liver, not reaching the chest cavity. The other 7 or 8 were all 'textbook' shots and I don't think any deer went more the 30 yards before dropping.
Since I woods hunt and my shots are close, I did switch from a 130 gr Sierra to a 150 gr Nosler solid base (now ballistic tip). But both bullets have worked well for me, but I feel the heavier bullet is less likely to break up if it hits bone.
I don't know about others, but when I'm in the process of actually shooting the deer, I not considering how I'm going to drag it out!
And I certainly can't choose the exact spot where I want my deer to fall.