Graybeard, the secret to shooting the Barnes bullets is, getting the bullets as close to the lands and groves as you can and still have the case feed properly.
I don't have much problems at all getting a good load, that is accurate in any of my guns using Barnes bullets.
JJHack's report is good information for thought, but my actual experience is different. Also I am not hunting African game, so I can't make the comparison, I am hunting North American game and getting an exit hole and good blood trails, but I never have to go more than 50 yards either. I don't think I ever went more than 50 yards. Most of the time I get the animal to drop in its tracks, or close to the spot it was shot, but not always.
Yes I am a Barnes bullet fan, because for me, they work and you can't argue with your personal experiences and success. I am not saying Barnes bullets are for everyone, but they work for me, and I will continue to use them no matter how many people tell me they are no good. When and if I experience bullet failure, on a consistent bases, I will then look for something better. Until then, my reloading bench will be full of them Barnes bullet boxes as it is now.
90% of my Rifles use Barnes bullets, 2 of my rifles use hard cast. My handguns use hard cast gas check bullets. But that is just my personal choice, I use what works.