I had a Ruger No.1 Varmint in .22-250 and got rid of it because of vertical stringing of groups and missing a number of shots because of that problem. I now know how to solve that problem by properly bedding the forend. For best results the TCR's may also need some forend work. Some were factory free-floated and some were not. All my TCR forends are now free-floated. That is, there should be not woood contact with the barrels. In that way point of impact is not effected by tension of the forend screw. Also, keep the hinge pin well lubricated for consistent shot to shot vibrations for best accuracy. A good bolt gun probably has better accuracy potential than either the No1 or the TCR, but either is plenty good enough for hunting. Also, a single shot is not much of a handicap for hunting. If one can't hit with the first shot at a standing animal, he probably can't make a second or third shot at a running animal. Full length resizing is needed for handloading with the TCR while the Ruger may only require neck sizing. Therefore brass will last longer for handloaders using the Ruger. For the hunter (except prairie dog shooters) this is not important and I think the TCR's break-over design is more convenient for hunting. That is, for safety it is easy to just break it open when one may slip like when crossing a fence or stream. I think it is faster and easier to load the TCR, except maybe off a bench rest. Extra barrels are an advantage of the TCR, including ones chambered for shotguns. If one gets creative and is willing to spend a little on gunsmithing, it is possible to have some barrels not available from the factory. For example I have a couple in .17 Hornet and one in .50-140 Sharps. I don't feel too bad about having gotten rid of the Ruger 1, but I will keep my TCR's and a pretty good assortment of barrels to go with them. There are a couple other advantanges of the TCR. Bore guides are available for bolt actions to protectect them while cleaning, but not for single shots. However, one can make a jig for cleaning TCR barrels. If high-mounted, big scopes are used on a TCR, one can have a buttstock with a cheek piece high enoug for good cheek support and still be able to clean barrels from the breech since barrels can be removed for cleaning.