Neck shots are pretty much all I take. Id say about 90% of the time for 25 years now. The past 4 or 5 years I have hunted exclusively with a .22 Hornet and every deer I shot with it was a neck shot. about 12 deer so far. Every single one dropped where they stood. longest shot about a 110 yds, closest was 11 yds. Nock on wood but i havent wounded one. Killed about 6 hogs with it as well, mostly head shots but some in the neck as well. My son took a 100 lb pig with a neck shot that missed the spine, still dropped right there, knocked out the juglars and throat and bled out quick.
I use to use a .243 for over 20 years, mostly neck shots as well, but it almost knocked their heads off. I saw a friend hit a doe in the neck with a 300 mag, it did knock the head off.
I always shoot off a rest or out of a box blind, in a box blind I rest the forearm on the window and I have the rear stock resting on a bipod, and I shoot over feeders 90% of the time. When I am about ready I grunt at the deer to get them to look up at me, then I smack em in the neck. I like them looking straight at me when I neck shoot them. I feel more confident with that shot than neck straight out.
I also have rattled in and killed several bucks, but they come in and are already looking at me, again I am shooting off a bipod in either prone or sitting position. 100 yds and under, its a neck shot 99% of the time.