Cast bullets will also be easier on the bore than jacketed bullets. As stated by others, 2400 will be easier on forcing cones than the ball powders like 296, H-110, etc. It will also be easier on the bore than very fast burning powders. With 2400 in your 357, small pistol primers will work, as will small magnum pistol primers, which I personally prefer ( in most calibers, my tests have shown ~50-125 fps increase in velocity with the magnum primers).
Having said all this, I personally use more jacketed bullets than cast, and although I use 2400 a lot, I also use a lot of 296 and H-110 in various calibers. Why? Because it takes a LOT of shooting to create significant throat and barrel erosion in a well built revolver. In almost 50 years of shooting big bores, I've "had" to have one rebarreled...a SBH after several years of very very heavy IHMSA competition and many thousands of rounds, all of it using 240 JHP's and 296. In fact, as it turned out, the new barrel shot no better than the eroded barrel, so I didn't really "have to" have it done!
I spent, and you will spend, more money on ammo than it will take to replace the gun, before you wear it out, with proper care.