This is my opinion only; based on what I have seen and experienced. H110 and W296 have variances between lots. Enough that each lot# has to be tested. So once you get your load with H110 for instance, the next time you buy your powder, it may perform differently. The next time you buy H110 it may not perform as well as it did the time before so it takes more or just the opposite, it takes less. I am only talking a tenth grain or three, but that makes a considerable difference when you are only using 10 grains to start with. It gets real critical when you are talking small amounts of it. If you look at load data from different sources that list both the powders, many times they have different amounts down as maximum. One time it may be that W296 will get more velocity than H110 with the same powder charge, some times it is reversed and some times it is the very same. I think it has to do with the particular lot that was tested at the time. Some powders are known for their consistency between lots. H322 is one of them and Bench Resters like it for that reason. They will have very little variation between lots so they can count on the next lot of H322 to perform nearly the same as the last one did. They may have to make just a small adjustment to get the same performance or none, but it will not vary much. VV N133 is another powder that has some consistency between lots and is gaining favor with the Bench Rest crowd. So I guess what I am saying is if you found H110 to be better than W296 when you tested, if you did it again with different lots of powders, you may find the same thing or you may find just the opposite. Maybe you have come to a different conclusion based on what you have experienced. This one thing I am sure of - just trying one lot of powder is not necessarily representative of what you will get in the future, especially with small capacity cases.