Here goes another vote for IMR 4350, 57 gr. IMR 4350 and 165 Nosler BT has accounted for many deer over the past ten years, shoots very accurately and holds together very well, despite the storied you may here, I've shot deer at enough different angles and ranges to tell you that if you put the bullet where you should, no matter the angle, it will penetrate through the vitals, even on two finishing shots I had to make for a friend that were Texas heart-shots, my least favorite, but it did the job. Also look at H380, won't get quite as much speed, but I purchased a surplus 8 lb. canister, and I found a good load for it with the 165 gr, and it meters so nicely, it's the only powder I use in my .308 and .243, so I figured, why not my .30-06? It works well also, but if you have 4350, go with that first.
Selmer