My CAS load is changing, but for years I have shot 7-1/2 gr of Unique with a 200 gr RNFP 44-40 bullet, either Bear Creek Moly coated or plain cast lead. I varied that occasionally from 7 to 8 grains, but stayed generally at 7-1/2, for a Yellowboy and a Henry. I have changed to Hogdon's Titegroup, 6 grains, and it works fine as well, and is a bit cleaner.