Take a look on the ammo sites for the ballistics of the round. If you are dead on at 50 yards you are about 10 inches low at 150, and have lost 2/3 energy. You need to decide if you want to take shots like that.
I use my Magnums (I have 4 so I must like them) for 75-100 yards. If it is longer than that and I have a choice then I will use one of my 17 rimfires, or my .204. I never would choose to hunt Coyote with it. Even chucks at over 100 yards I will take a centerfire and pin them good.