Don't worry about it, I have a bunch that are off center, some by a lot, but they shoot just fine, no different than those that are centered or just a little off center. as I posted before when you brought this issue up in another thread, my .444 has off center strikes and is one of the most consistently accurate H&Rs I own. I suppose the anvil configuration on some primers might be a problem for a really off center pin strike, if they are, just don't use those primers!!
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I'd say not following thru with trigger pull would be more to blame for inconsistent accuracy. If it's off center bad enough to cause misfires, H&R will replace the barrel.
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Tim
Check the firing pin if it is off center very much it will cause erratic groups.Please let us know if it is off center.