The advantage of the WLN over an LFN is that the WLN allows maximum powder room, which gives maximum possible power, while the wide meplat delivers that power quite a bit more severely than the LFN. The WLN is ONLY for heavier bullet weights. The WFN has the same meplat size as the WLN, but the nose must be shorter to avoid having excessive unlubricated bearing surface outside the case, which makes it most suitible for medium to light weight bullets. Be aware when I speak of bullet weights I'm speaking of the offerings in the LBT catalog, not standard jacketed bullet weights.
For 41 caliber I don't like to sell the LFN for game, because of the small meplat, but as caliber goes up the difference in impact between the LFN and WLN/WFN gets narrower. Mr Fowler didn't state anything about calibers he has used, and doesn't see a great difference in killing power between the LFN and the wider meplat bullets, but I would estimate that 95% of my customers would argue that, as I would.
If the middle weight WFN's are used, and if the bullets are properly fitted to the revolver per my recommendations, I don't believe many people can see a difference in accuracy between LFN and WFN out to 100 yards, but at longer range the LFN will be more precise due to its better flight form. If heavy weights are compared, LFN vs WLN the LFN will definately be most accurate at the longer ranges especially. However most revolvers WHEN PROPERLY SET UP AND FITTED PER MY SPECIFICATIONS, AND IF THE CASTER DOES A GOOD JOB OF VISUAL BULLET INSPECTION, will put most of the bullet weights and profiles I sell into 2 inches at 100 yards. (Notice I leaned hard on visual inspection. Weight sorting is not needed or benificial if all bullets look real good.)
Ross Seyfried wrote up an artical for Guns and Ammo sometime in the 90's on revolver accuracy. In it he used a 45 colt Ruger Bisley loaded with my 325 gr WFN, gas checked, to 1450 fps as I recall. He was able to print groups that could be covered completely with a standard size postage stamp, at 100 yards. He fitted the gun and bullets exactly to my specs.
What I'm saying here is, get a bullet that kills the best, do your homework, and it will make you happy in the accuracy department, and on game.
As for bullet weights. ---- When I developed the line of LBT bullets there was quite a rage for maximum power and weight, and there was really nothing available in heavy weights that performed well and at safe pressures. I spent a lot of months developing the most efficient power getting bullets ever, and have over the years since, decided that most people are far better off using the middle weight bullets, and at that, not driving them too fast, as too much power causes too much recoil for most shooters, which hurts their accuracy potential so badly that the power is worthless. When making a determination as to what speed to drive them, use my Displacement Velocity formula and stay over 100 and under 130.