No you cannot. The Lee Loader is a neat little kit that will only load one caliber. If you need another caliber, you have to buy another kit. If you think you are going to reload more than one caliber, you would be better served by buying one of the starter kits with a press and some dies. Much more versatile, and cheaper in the long run. If you are only going to do one caliber, and it is currently made by Lee, it is fine for a starting point. I have several, but I wouldn't spend the money if reloading was something I knew I was going to be doing very much of. If you only shoot a limited amount each year, might be fine, but if you do any volume at all, it can get old quick. I keep them more as a novelty than any thing else. They work, but I would save for better. Just so you know too, Midway has them for 18.99. HTH, Billy