Here's my side of it. I shoot a .25-06 in a Ruger M77MkII.
After a few years of experimentation, the best combination I've found is a Winchester Large Rifle primer with H4831SC (117 gr. Hndy BTSP) for accuracy - 3/4" at 100 yds. For a hunting round, I'll switch the primer to a Federal 210. My groups don't enlarge that much, and my velocity is pushing 2990 fps. Group size with this is .75 to .90 of an inch.
R-22 seemed to be the answer, at first. But I couldn't get the power curve of the energy on top of the accuracy curve. Meaning that I had great accuracy at 26-2700 fps, but lost all accuracy when close to 3000 fps. The switch to from R-22 to H4831SC with a Federal 210 primer (much hotter than WLR) seems to have solved this problem.
This winter (December Whitetail hunt in the Central Arizona Mountains) I'll keep the powder and primer, and switch the bullet from a 117 gr. Hndy BTSP to a 117 gr. Hndy SST. I expect that to tighten up the grouping a little more also.
I hope this helps. BTW - except for the Federal 210 primer, all of the loads at the given velocitys can be found in the Hornady Reloading Manual. They use a WLR in that.
Good Luck. :-)
P.S. How did I figure this one out? By shooting comparable loads with Sierra 117 gr. bullets and their data and doing a little interpretation. I really wanted to use the Hornady line of bullets though, because they can be easily swapped for each load. BTSP for SST for the new Interbond (supposed to be coming out in .257) without having to work out new loads for each. Sierra, by contrast, only offers one style per weight. Don't know about Nosler or Swift. Speer didn't have anything in a 117 gr. , and the results from the 120's were abyssmal.