Swampman,
I use the Lee REAL mold in my 50 cal. (320) grn. with good success. I lube with wonderlube or Crisco. The only problem is that you have to push them fast enough or they will tumble. I shoot loose powder, 85 grns., I get 1.5" avg. groups at 100 yds. from a 1 in 28 twist barrel. I tried them in my traditional with a 1 in 48 with poor results.
I drop in water and use them just as they come from the mold, with lube added of course.
Ben