I have the 454 and have found it to shoot very well and it is extremely accurate. I have close to 500 full power rounds through it and about half that in standard loads if you can call a 260gr JHP or Cast Performance moving at 1850 fps standard.
I have not had any issues with it so far and everything still locks up good and tight. I am used to carrying big handguns so that isn't an issue for hunting with it. I use a Bianchi holster and carry it in cross draw fashion. It makes drawing and getting on target much faster with the longer barrel.
I would imagine that the 44 version would also be very suitable for hunting, however I would stick with the sights and forgo the scope. I shot a scoped Redhawk in 44 for several years and granted it shot great, I have done MUCH better with it since removing the scope. It helps out much more with the balance and quick acquisition of targets.
My only fault of the Taurus Raging Bull is the lack of sight options for them. The standard ones are a bit much for cutting a fine line at distance, but are great for anything 50yds and closer.