My first .22 pistol was a S&W 2206. Still have it, and it's a great gun. Later bought a Mk. II and it was a real hemorrhoid. Traded it for a .22 SP101. Add to that a S&W 17, 617 and a .22 Bisley, and I am really sold on revolvers. Accurate, don't jam, shoot anything, and you don't tend to run through the ammo as fast. The dark side - they're expensive compared to an auto.
I've heard mostly good about Rugers, however, I have heard of some who were not satisfied, and I had a lot of problems with mine.
I have not heard any negative things from Browning owners, though there have been a lot fewer of them.
If I were to buy another auto (though not very likely), I think I'd try that Browning Buck Mark Micro with the 4" barrel . . .