There is no such thing as a stupid question if one doesn't know the answer, but there is such a thing is a whole bunch of stupid answers, which I just deleted a bunch of. - Perhaps when you read anyones answer in the future, if they have a bunch of peripeheral nonsense which is supposed to make them look brilliant, ignore the whole packet. If someone knows what they are talking about, regarding mechanical things, the answer is best just given as simply as possible.
Your gun will shoot PROPERLY fitted cast bullets as well as it shoots those lightweight jacketed. At worst the bore may need to be lapped. For the cartridges which have only a taper into the rifling for a throat, like 45-70, 38-55, 30-30, etc, the bullet must be held precisely in the chamber to get a precise start down the barrel. In other words, the first priority is to get a bullet that makes the cartridge fill the chamber. This will almost certainly be way over groove diameter, which will not change pressure with cast bullets. To determine what maximum bullet diameter should be, just measure the case neck of a few of the fired rounds that you are using. The difference in diameter between new and unfired cases can be added to diameter of the bullets in the new ammo and you'll have the diameter which will shoot most accurately. Since cases spring back a little, this will allow enough space for easy chambering.
If you don't care for speeds over about 1500 fps, a plain base bullet will probably keep you real happy, but the barrel will almost certainly require lapping. If you use gas checked bullets, you'll get more forgiveness for a rough barrel, but even so, lapping will deliver you a match grade barrel which gives optimum accuracy.
If you decide to lap the barrel, get the LBT lap kit and a pack of 45 rifle push through slugs so you can measure progress and know when the barrel is perfect. When finished, one of the push through slugs will give you an exact measurement of the barrels inner diameter. However, barrel diameter can be ignored as long as it is smaller than the bullet that gives you a close chamber fit.