Since this thread started as windage and rifling I thought I would add my two cents. For rifled barrels the windage only has to be large enough to safely seat the projectile without it hanging up in the bore. Reducing the windage will increase the accuracy, just don't reduce it to the point that it gets stuck in the bore. This is the main reason for bore gages, usually a section of the rifling. Do not worry about increasing pressures. Think about the Parrott round that has a cup that seals the bore as it expands into the rifling, or the Hotchkiss round that has a lead band that seals the bore as it is forced into the rifling, or the Schenkle round that has paper mache forced into the rifling, and I am sure that there are others.
Having said that, the testing that I helped Matt Switlik and Don Lutz with showed that lugged rounds got a higher velocity with lower pressures than the same weight projectile with a saboted (cupped) base. So if you are interested in lower pressures develop a lugged round.
I guess this was more than two cents.