What caliber are you going to hunt with?
IMO, the best bullet is also the simplest, at least for the larger calibers. Just find a suitable wieght hard cast lead bullet with a large meplat and load it appropriately.
A word of caution though. Don't load lead bullets with the same powder charges you would use with same wieght jacketed bullets. The lead seals with the bore better and you will achieve better velocities with less powder than you will with jacketed bullets, or at least that's been my experience.
Take care,
~Rat