Cast boolets from a 45 ACP - way too much fun to ever stop. Some folk carry cast for personal defense or hunting. Some folk won't carry jacketed at all. My preferred cast bullet is the old Lyman 452423, a 238 gn swc designed by Elmer Keith for the 45 Auto Rim.
Cleaning - a necessity regardless of what you shoot. Proper loading helps reduce lead fouling. There are some powders that love cast bullets and some that do not. Unique, WW231, Titegroup (I think), Bullseye, Red Dot, SR4756 all good for cast. Cleaning your barrel - wrap some screening wire tightly around a bore brush and that will get your lead out.
Cleaning reloading dies - use some whiteout to mark the threaded seating die punch/bullet seater depth when you clean your die - the seating die is the only one I have had to clean if using cast bullets, and if you bell the mouth of the case enough you may not have to clean the seating die much, or often.
Yeah, cast bullets from a 45 are way too much fun to stop. jmtcw.