The manufacturor is different.
IMR 4350 is made by DuPont.
H4350 is made by Hodgdon.
AA4350 is made by Accurate Arms.
All different. All are manufacturor attempts at duplicating the original military 4350 powder. Not exactly the same....close....but not close enough to interchange. You can use one in place of another, but you do HAVE to follow the book suggestion for starting loads and work you way up to your load. You cannot interchange them.
I have some original surplus Military powder. Not H and not IMR. I have to use 2.0-2.5 grains more of this powder to get up to velocities I had with H. If you were to go in reverse order and try to relace the Military powder with same charge of H or IMR powder, you would be 2.0-2.5 grains above a book load. You can see how disasterous this could become.
Chevrolet and GMC. Ford and Mercury. Models can be close, but very different.
Steve