My Ruger single six comes with two cylinders one for the .22 lr and the other for the .22mag
they both shoot very accuretly in this old revolver, I had once mistakenly left the mag cylinder in and loaded .22Lrs, it shot accuretly, it was when extracting the empty's that I noticed bulged cases and one or two were split at the mouth the cases, Im not going to condone openly that every body shoot them in every .22mag they own all the time, But mistakes happen and they do work without damageing my revolver or me. and that day I did bag 3 ptarmagin useing .22lr's in that magnum cylinder.