I love my S&W revolvers, and I've got a bunch of them, but I'm going to recommend something else — a 3" Ruger SP101 in .357. It's big enough to take to the range and target shoot with .38s, or .357s. It handles them both well. It is also small enough to carry concealed if later you and/or your wife gets a carry permit. My wife got one about 14 years ago, and she loves it. It was simple for her to learn on (no magazines, jams, etc.) and the grip fit her hand well (again, no magazine running through the middle of it). Now she has the CT Laser grip, but that's because she doesn't see as well as she used to.
S&W has dropped the K-frame revolvers, but you may still find a model 19 or 66 out there with a 2.5" or 3" barrel, but I really think the little Ruger is one of the finest handguns ever made. It will need a trigger job, but it's a tank that can handle any load you put through it, and is not punishing to shoot. Accurate, too. When my wife took her training class, she was hitting drop targets and 30 and 40 yards with it. No one told her that was hard to do. Her instructor said do it, and she did. (What a gal!) The 3" barrel is a great all purpose length. Long enough to sight down it well, and yet short enough to hide if you need to.
Just a thought. Check it out before you make a final decision. It was the first centerfire gun we ever bought, and 30 guns later, it would be the last one we'd have if we had to sell the rest. (I even have one in .22 LR, too.)
And speaking of .22s, yes, with the price of ammo today, you're gonna need one for fun and practice, too! But that's another thread!