CK, years back, picked up a lb. each of the H4227, and the IMR4227, just to see what would give me better accuracy. Turned out it was the H4227, so picked up an 8lb. keg. Different lot number. Accuracy wasn't nearly as good, so, of all things, ended up using W296. Anyway, point is, if you find one your happy with, get enough to last awhile. I can tell you that the H110 seems to burn alot cleaner than either of the 4227 powders. And if you contact the powder company's, they'll send you one of their small reloading manuals. Isn't quite as complete as one of the bigf one's, but will give you enough info on all the standard calibers. gypsyman