I have to agree. If you are shooting long ranges, I wouldn't be using heavy conicals. For that I would be using a saboted bullet combo. But when using conicals, for an area in the less then 100 yard range, magnum amounts of powder will only destroy your shoulder and not be any more accurate or effective then the lower charges.
I normally use no more then 80 to 85 grs of subs and no more then 75 grs of the real stuff (Goex FFg). Within the ranges that I hunt in thick brush here in Va., that is more then enough to harvest any game in my area.
Now if you are constantly shooting in the 150+ yds range, then go to sabots and 100 to 150 grs. of powder. this will then help you in reaching out and touching that special deer for you freezer.
Also remember these are just my thoughts and will probably be different from those of my fellow hunters. Not everyone is the same.