I've never seen a panther but I've heard from 3 people that insist they have seen or know others that say they have seen one. All of the unconfirmed sightings come from the Honey Island Swamp, a huge swamp in SE Louisiana. Of course this is the same swamp (not the same people) from which Big-Foot sightings have allegedly come. So, I take all such information with a grain of salt.
As I said, I've never seen one but I did have an experience that gave me goose bumps. I hunt in SW MS on about 110 acres, which are owned by my hunting buddy. Anyway, one evening just before I got out of my stand (legal shooting hours were just about up and it was getting dark fast), I heard what to me sounded like a baby being boiled in oil. That is the only time I've ever heard something like that. When I got to the camp, I asked my buddy about it and he told me it could have been a panther. Maybe, maybe not.
Finally, several years ago, my buddy was checking the barbed-wire fence around his property, when he noticed what he described to me as a large cat footprint. It had recently rained and the ground was soft. He described it to me as a possible cougar print. A neighbor of his was with him when this occurred and confirmed it as well. Whether it was in fact a cougar print, I really don't know. All I know is that I've never seen either a cougar or black panther while I've hunted there and I've been doing it for 15 or so years. Just for the record, my buddy is not one to make up stories.