S.B.,
I have a friend that uses them in his Ruger MKII. I tried them in a smooth bore .22 rifle for rattlesnakes but had lots of trouble getting penetration with that small #12 shot. My friend shoots them as long as they move, sometimes a whole magazine worth. Me, I don't have time to wait around. I want them dead on the first shot. For rattlesnakes, DEADER IS BETTER. Lawdog