I have a Remington 7600 Carbine .35 Rem that loves the 150 gr load. I would have never bought this ammo for deer hunting but somebody gave me a few boxes and they shot so well in the 7600 that I decided to try them on deer. Season before last I shot a decent 150 lb 8 point at about 40 yards. He swapped ends and crashed within another 40 yards. The bullet basically turned inside out, expanded almost down to the base and came to a rest behind the off-side shoulder. I couldn't find fault with its performance and wouldn't hesitate to use it again on deer in that weight class because it did what it was designed to do and killed cleanly. It would not be my pick for overgrown deer, hogs and certainly not bears. After my small stock of the 150s is exhausted I'll likely go to the traditional 200 gr RN because I much prefer an exit but I wouldn't lose any sleep using the 150s, based on results on that one deer, whatever that's worth.