Have used the heavy for caliber 223s as well as the 243 100gr on windy days and of the two I will take the 243 as my first choice.
I was of the opinion the .243 Handis had issues with consistency in accuracy from one rifle to another that made buying one a crap shoot.
No worse than some of the other Handi calibers, ie: changing twist rates and not telling anyone, long troughs, FTFs, tight spots in the barrel, poor shelf and latch engagement.
We have all had or read about all these things and more with the Handis and with other brands of firearms as well.
We either live with them, fix them, or get rid of them and try something else.
My 243 Handi shot great right out of the box as has most of my Handis.
Don't care for the heavy bullets in the 223.
I just move up to the next caliber.
Standard weight bullets in the 223 does just fine for what I use them for.
I definitely want to avoid any risk of leaving an injured one alive. Coyotes can be dangerous when healthy, hurt would be a real risk.
They will all kill, just some more reliably than others.
To each his own, that is why they make so many different calibers and loadings for each!