FL sizing is a little tough on rifle cartridges but I use it for neck sizing/depriming and bullet seating/crimping.
To your question I also do all my pistol loading on the Lee hand press, 44, 380, and now 357.
It will do fine on your pistol ammo.
I like it. And I keep it and all of it's peripherals in a tackle box in the closet. When I need it I have the hand press, primer, scale, dies, and bullets and powder all in the box.
Bang out 50, and put it all away when I am done.