Personally, I have never had a Nosler Partition, in any caliber 243/7mm/.30, fail.
In fact, I have had cases where the bullet preformed way beyond expectations.
One case with the 243, was a raking shot, with the deer quartering away.
The shot hit far enough back to cause a mess through the intestional track, but didn't.
There were nice little 24caliber holes through a number of guts and blown up lungs on the other end. How or why, I have no idea, but I was happy.
I have also seen hits over the years, mine or others where the Nosler did it's job but wasn't excessive in the damage department as would have been normal with a typical cup an core bullet.
Does/can a Nosler Partition tear things up? Yes, how could it not an still do it's job, but by not flying completely apart it is not excessive.
I realise we are blessed with a number of quality bullets in these days, but Nosler Partitions are one of the great ones.
As per expansion with the 243 in deer sized critters, it is great, and pass thru will depend on where and what you hit.
I once took a whitetail doe head on and found the bullet almost at the skin on the other end and that was with a 300 win. mag. - 165gr Nosler Partition at better then 3200fps/muzzle.
I first started using the Nosler 95gr Partition, but have used the 100gr with great results in all department.
My 243 is currently still shooting Noslers, but now the 55gr Balistic Tips in the 3700 - 4000fps range and not for deer, while my go to hunting rifle for deer, elk and anything else I have tags for is the 300win. mag/165gr Nosler Partition.
Ain't no such a thing as "too dead"!
Keep em coming!
CDOC