Is this a recipe you got from a reloading manual? If not I wouldn't use it till you checked it out in a reloading manual. I have no personal experience using unique in 9mm, so I'm unsure of the load that you are using.
That all being said, from my experiences, the best accuracy I've ever achieved in many of my straight wall rifle rounds was where the powder was either slightly compressed or just right at the base of the bullet. From what I've been told, and read, is that with a full case it allows for the most consistent ignition and burn of the powder since it's not moving around in the case. That is not to say try to fill every case to the max with powder because that is dangerous. Some powders simply can't be loaded with that much powder because it would be to much powder, and to much pressure.
Again, check it out in a reloading manual. Personally I would start out at a starting load and work up.