I live in N.W. Ontario , Canada , and have used the 35 Whelen a fair bit here for deer and moose hunting... I was amazed when I started using the Whelen instead of the 30-06. The big 35 with almost the same paper ballistics as the 30-06 is the hands down winner... That larger diameter bullet is the key - it imparts the energy much more efficiently... You have to see the difference to really get the picture of how different these two cartiidges behave...I started using the factory Rem 200 gr SP bullet for hunting as it was the only ammo available here , and that ballistic SD inferior bullet just floored moose like nobodies business.. One in the tracks kill , and one moose I shot was standing in timber 60 yds away, I shot through a six inch Poplar treee (which I did not see actulally) and rolled the moose over - dead.... One moose I shot with a Hornady 250 gr RN bullet , a handload at 2400 fps I hit in the front of the chest as it faced me 160 yds away. The bullet was found in the rump (rump roast that was), a perfect mushroom...That was an instant kill by the way , the moose collapsed straight down with it's legs folded under it - we had to push it over to clean it!...The Wheln kills game all out of proportion to what you think it would with it's '06 sized case , hunters are really missing out on a great calibre for N.A. hunting , it should have a much larger following - but the magnum craze simply pushed it aside promoting velocity as the be-all-and-end-all.... A heavy bullet of large diameter at moderate velocity is a sure proven performer on big game , the bullet behave as they were intended too - more reliably than ultra high velocity projectiles... The biggest problem I see now with hunters is that they choose a super premium bullet for deer sized game when they don't need it... The smaller thin skinned game shot with these high tech bullets simply pass through , and allow the game to run off to die far away where the hunter can't locate them... The Remington Core-Lokt and Hornady Interlock bullet are good bullets for most N.A. hunting..I really like the Hornady SST bullet to for longer range shooting... Of course tho , when you factor in the big bears , thats where the premium bullets really show their worth..
These are just my thoughts and opinions - based on limited experience , but it sure worked for me... So I would sum things up by saying the 35 Whelen would be fine for all lower 48 hunting...And for Canada and Alaska , the great 9.3x62 Mauser with it's 286 gr bullet would be just about the perfect calibre!...... God Bless and good hunting..... Bob