I've never had a bullet fail yet. Whether it is a sierra, hornady, rimington, or anything else. If you hit a deer in the chest, they won't go far. I have killed several deer with my .25-06 encore using 85gr. ballistic silver tips. And they are pretty weeney compared to the 165gr. But they have never failed. Here is a pic. of the last doe I shot at 250 yards.