are you talking about the .410/.45 lc? or just a .410 shotgun? if its just a .410 shotgun then no in no way should you shoot a .45-70 through a .410 there really no way to do it your talking about a .45 caliber bullet going through a .41 caliber or smaller (with choke) same with a .45lc through a regular .410 not going to work bad idea. if your talking about the .410/.45 lc (which is desgined to shoot both) i dont think you can shoot a .45-70 in it i think the case is to big? dont know though probably a bad idea either way